References in periodicals archive ?
The primary objective of the study was to evaluate the safety, tolerability and pharmacokinetics of single and multiple ascending doses of CH-4051 in healthy male volunteers and to determine the maximally tolerated dose (MTD).
This data suggests that the exercise regimen was well tolerated and safe for these participants, and that if low levels of aerobic activity increase one's ability to maintain an exercise regimen, they by all means should be employed as an effective rehabilitation measure.
In the phase 2 portion of the study six patients were treated at the maximal tolerated dose (MTD), HHT 1.
The study concluded that a dose of KOS-862 100mg/m2 given weekly three out of four weeks was well tolerated and was associated with only mild to moderate toxicity.
In our high schools, homosexual propaganda is tolerated if not promoted.
What's incredible, however, is that it is the first time in the department's history that officers are routinely dismissed for committing serious offenses, especially for excessive use of force against citizens, a crime that was routinely tolerated before the Rodney King videotaped beating.
Of the 34 who completed the experimental protocol, 28 tolerated the full doses of chemotherapy and radiation.
Disagreement is not tolerated, and there can be no debate or compromise.
And when behavior passes the corner on rude and pushes into aggressive, loud and obnoxious, it simply cannot be tolerated in the City of Angels.
If significant side effects occur at any dose level, the study will end and the previous dose level will be considered to be the maximum tolerated dose.
A primary objective of the trial is to determine the maximum tolerated dose (MTD) of huN901-DM1 in multiple myeloma patients with this dosing schedule.