com/reports/c47910) has announced the addition of Toxicity
Biomarkers: Promising Tools for Accelerated Drug Development to their offering.
The third project is a collaboration with the University of North Carolina at Chapel Hill and the NIEHS to examine nuclear receptor--mediated toxicity
and oxidative damage in mouse and human cells in the liver bioreactor.
They place a few drops of a suspected toxin, dissolved in saline, on the exposed membrane and measure the amount of blood-vessel breakdown as an indicator of toxicity
Mutagenicity and in vivo toxicity
of combined particulate and semivolatile organic fractions of gasoline and diesel engine emissions.
Krom says the observed toxicity
is most likely related to the blood transport mechanisms that carry cyclosporine, which binds to lipids.
Many chapters relating the use of arrays to evaluate toxicity
issues are well written.
In this way, abnormal ratios of porphyrins in the body not only signal a chemical's enzymatic site of action, but also might serve as an earlywarning flag of ongoing low-dose toxicity
These experiments were not designed to assess concentration additivity, so no judgment can be made either in favor of or against the possibility that the toxicity
of the mixture represented concentration additivity.
Subsequently, they have confirmed that the customized DNA microarray can be used to evaluate toxicity
The differences between engineered nanoparticles and other materials, as well as distinctions among nanoparticles, add to the challenge of assessing their toxicity
1) However, the most severe and potentially life threatening of these side effects is the development of pulmonary toxicity
Since comprehensive coverage of the topic of the reproductive toxicity
of metals is beyond the scope of this volume, editor Golub (environmental toxicology, U.