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Antigenic modules in the N-terminal S1 region of the transmissible gastroenteritis virus spike protein.
Critical epitopes in transmissible gastroenteritis virus neutralization.
Recombinant canine coronaviruses related to transmissible gastroenteritis virus of swine are circulating in dogs.
Two amino acid changes at the N-terminus of transmissible gastroenteritis coronavirus spike protein result in the loss of enteric tropism.
Swine can host several coronaviruses (hemagglutinating encephalomyelitis virus, transmissible gastroenteritis virus [TGEV], and porcine respiratory coronavirus [PRCV]).
Together with porcine Transmissible gastroenteritis virus (TGEV), canine coronavirus, and human coronavirus 229E (HCV), the feline coronaviruses form a separate cluster within, the genus Coronavirus, including Feline enteric coronavirus, and FIPV (26).

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