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| Hemodynamic benefits were also realized in important secondary endpoints, including pulmonary capillary wedge pressure (PCWP). A decrease in pulmonary capillary wedge pressure (PCWP), a measure of the blood pressure in the heart that when elevated, forces fluid into the lungs causing respiratory problems (the primary endpoint). CPC-111 has now demonstrated positive effects on numerous efficacy parameters in CABG patients, indices of both heart damage such as CKMB levels and a variety of heart function measures such as cardiac index, left ventricular stroke work index, pulmonary artery wedge pressure and, most recently, pulmonary vascular resistance. |
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