It is used in different form to improve the wound healing, enhancing the rate of wound contraction
and reducing scar formation.
Note the evolution of wound contraction
in a 10-day interval until completely closed at 60 [+ or -] 3.
Excision wound model was used to study the effect of drugs on the rate of wound contraction
and time required for full epithelization of the wound.
Macroscopic evaluation was performed on the tissues of lesion to verify wound contraction
regarding measurements performed on the day of surgery.
The wound contraction
was evaluated and the wound area measured at the end of the experimental period, that is, day 14.
The Study showed that topical application resulted in an improved wound contraction
rate and considerable healing time reduction compared with that of the control group, These results may be attributed to the enhanced wound healing progression and the display of noticeable wound margin hydration resulting from tissue regeneration.
Difference of Per cent Wound Contraction
between Days and Treatment using Multivariate test DEPENDENT VARIABLE: Per cent Contraction Value F P value Remarks Day Pillai's Trace .
When grafted to the extensive wounds such as burn wounds, the tissue engineered matrix containing bone marrow derived cells showed better healing and keratinization, less wound contraction
, and more vascularization .
rate, epithelialisation period, and malondialdehyde (MDA) level were the parameters used for selection of single dose of F1 and F3 for comparative study of wound healing on excision wound model.
In rats'excision wound model, wound contraction
and period of epithelization were measured.
14,21 On 6th day, it was more obvious in scalpel group in our study and resulted in more wound contraction
and ugly looking scar as compare to CO2 Laser groups.
Also in the extract-treated wounds indicated that epithelialize faster, and the rate of wound contraction
was significantly increased in comparison to control wounds.