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Related to ACE inhibitor: Angiotensin receptor blocker, Beta blockers
See: deterrent
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The risk for coronary heart disease was 26%-28% higher on placebo than on an ACE inhibitor.
The ACE inhibitors that do not cross the blood-brain barrier are enalapril, benazepril, moexipril, and quinapril.
Many physicians, perhaps the majority, behave as if they believed that ARBs are preferred to ACE inhibitors.
A 2011 meta-analysis of 5 RCTs (total 2975 patients) that compared ACE inhibitor therapy with placebo in diabetic patients without hypertension and albuminuria found that ACE inhibitors reduced the risk of new-onset microalbuminuria or macroalbuminuria by 18% (relative risk [RR]=0.
Yancy recommend that the ARNI replace an ACE inhibitor or an ARB for patients tolerating these therapies alongside standard care.
ACE inhibitors are typically well tolerated, but may cause a dry cough, and elevated potassium levels (hyperkalemia).
ACE inhibitors are among the most commonly prescribed medications worldwide because they are indicated in the management of hypertension, congestive heart failure, myocardial infarction, diabetic nephropathy, and chronic kidney disease.
Angioedema usually develops in the first few hours or days of initiating an ACE inhibitor (Adams et al.
Typical scenario: A patient has diabetes and is on an ACE inhibitor with persistent microalbuminuria.
Also, the percentage of patients who withdrew from ACE inhibitor therapy due to cough from enalapril was higher in the study (2.
And it was better than an ACE inhibitor in preventing stroke and heart disease.