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Metabolic activation of bromodichloromethane by GSTT1 may result in the formation of 8-oxo-guanidine DNA adducts that are repaired by base-excision repair through the expression of genes such as OGG1 (8-oxoguanine DNA glycosylase), APEX1 [APEX nuclease (multifunctional DNA repair enzyme) 1], and XRGC1 (X-ray repair complementing defective repair in Chinese hamster cells 1).