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The researchers used three control groups to confirm their findings: 21 of 22 subjects who tested positive for the disease also had the antigen-antibody complex; all 19 controls with other diseases did not have the complex, and four of 12 controls with no rash but with other symptoms, and who tested negative for the disease, had the antigen-antibody complex.
Tumor antigen 90 (TA-90), a 90-kd glycoprotein, appears on the surface of melanoma cells and can be identified using an enzyme-linked immunoassay for the TA90 antigen-antibody complex in blood, said Dr.