10.37 [+ or -] 5.49, p = 0.01) and were stronger correlated apnea-hypopnea index
assessed with portable device .
Out of 48 patients 7(14%), 3(6%), 2(4%), 1(2%) patients in the age group of 20-40 had apnea-hypopnea index
less than 5, 5-14, 15-29 and equal or more than 30 respectively, similarly 16(32%), 5(10%), 4(8%), 2(4%) patients in the age group of 40-60 had apnea-hypopnea index
less than 5, 5-14, 15-29 and equal or more than 30 respectively.
Major finding: Nearly half (49%) of the 45 patients receiving active treatment with the device had an apnea-hypopnea index
that was lower than 5, compared with 11% of those using the placebo device, for an odds ratio of 7.8 and a number needed to treat of 3.
In adults, an apnea-hypopnea index
(AHI) of greater than or equal to 5 is the minimum criterion for establishing a sleep-disordered breathing diagnosis, while severity is classified by the number of events per hour.
There was no significant difference between the young and middle-aged OSA groups in apnea-hypopnea index
. The middle-aged OSA group, relative to the other groups, showed decreased activation by fMRI in the task-related brain regions.
Spearman correlation analysis between the QTD, QTcD and Apnea-Hypopnea Index
did not show any significant correlations (Fig.
Previous studies have shown that the apnea-hypopnea index
(AHI), the most widely used measure of sleep apnea severity, is linked to mortality and heart disease.
Using standard criteria, both recordings were scored for obstructive and central disordered breathing events, and the apnea-hypopnea index
(AHI) was determined.
Measurement of the number of apnea and hypopnea events per hour, which is called the apnea-hypopnea index
(AHI), is used to grade OSA (7).
Treatment success was defined as a [greater than or equal to] 50% reduction from baseline in the apnea-hypopnea index
(AHI) or AHI <10 when wearing MAD.
Several treatments, notably continuous positive airway pressure and mandibular advancement devices, did improve intermediate outcomes such as scores on the apnea-hypopnea index
, scores on the Epworth Sleepiness Scale, and blood pressure levels, but the evidence did not show that this in turn improved mortality, cardiovascular events, or the other "hard" outcomes of interest, Dr.
(5) On the other hand, in cases where a patient has an Apnea-Hypopnea Index
(AHI; used to indicate the severity of sleep apnea) score of more than five, a positive ESAP has a predictive power of 100%.