References in periodicals archive ?
Oral aprepitant is under study in several ongoing phase II clinical trials for treatment of severe pruritus resulting from targeted biologic therapies for various cancers.
Palonosetron and aprepitant for the prevention of postoperative nausea and vomiting in patients indicated for laparoscopic gynaecologic surgery: a double-blind randomised trial.
y se debe actualizar la revision sistematica existente sobre el aprepitant (20) ya que se dispone de nuevas evidencias (21-25): ademas, no se ha comparado sistematicamente su eficacia con la de otros antagonistas del receptor de la NK-l y existe controversia para la prevencion de la nausea postoperatoria con el aprepitant (22), por lo que se llevaron a cabo una nueva revision sistematica y un metaanalisis.
Combined data from two fase III trials of the NK1 antagonist aprepitant plus a 5HT 3 antagonist and a corticosteroid for prevention of chemotherapy-induced nausea and vomiting: effect of gender on treatment response.
27) The physiological basis of this risk is demonstrated by the effectiveness of aprepitant, an NK1/S-P inhibitor drug.
The present study was performed to evaluate the potential effect of aprepitant 40 mg on CYP2C9 activity and to evaluate the safety and tolerability of coadministration of aprepitant 40 mg and tolbutamide 500 mg.
The newest antiemetic drug is aprepitant (Emend[R]), the first and only neurokinin-1 receptor antagonist available.
and administer two additional medications to prevent nausea: Zofran (ondansetron) and aprepitant.
a 3-drug combination of 5HT3 serotonin receptor antagonist, dexamethasone and aprepitant on day 1 for chemotherapy agents with a high emetic risk, e.
1] desarrollado clinicamente, el compuesto denominado MK0869 Aprepitant, fue probado en un principio en pacientes con depresion mayor y elevados grados de ansiedad (17).
Por fortuna, especialistas en oncologia nacionales e internacionales presentaron Aprepitant, medicamento que previene la nausea y el vomito en pacientes con cancer que son tratados con quimioterapia.