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Watchful attention; custody; diligence; concern; caution; as opposed to Negligence or carelessness.

In the law of negligence, the standard of reasonable conduct determines the amount of care to be exercised in a situation. The care taken must be proportional to the apparent risk. As danger increases, commensurate caution must be observed.

Slight care is the care persons of ordinary prudence generally exercise in regard to their personal affairs of minimal importance.

Reasonable care, also known as ordinary care, is the degree of care, diligence, or precaution that may fairly, ordinarily, and properly be expected or required in consideration of the nature of the action, the subject matter, and the surrounding circumstances.

Great care is the degree of care that persons of ordinary prudence usually exercise with respect to their personal affairs of great importance.

Another type of care is that which a fiduciary—a person having a duty, created by his or her undertaking, to act primarily for another's benefit—exercises in regard to valuable possessions entrusted to him or her by another.


n. in law, to be attentive, prudent and vigilant. Essentially, care (and careful) means that a person does everything he/she is supposed to do (to prevent an accident). It is the opposite of negligence (and negligent), which makes the responsible person liable for damages to persons injured. If a person "exercises care," a court cannot find him/her responsible for damages from an accident in which he/she is involved. (See: careless)


(Be cautious), verb be cautious, be concerned, bear in mind, beware, consider, curare, give heed to, guard, have regard, heed, look out for, mind, pay attention to, protect, take precautions, watch out for, watch over
Associated concepts: care and caution, care and skill, careful, careless, degree of care, due care, extraordinary care, great care, lack of care, ordinary care, slight care, want of care


(Regard), verb administer to, attend, attend to, be concerned, be concerned for, become involved, bother, foster, mind, minister to, nurture, pay attention to, serve, supervise, support, sustain, tend, watch over
Associated concepts: care and custody, care and mainteeance, custody or control
See also: administration, agency, aid, alimony, apprehension, assistance, auspices, burden, caution, charge, concern, consideration, constraint, control, custody, direction, discretion, fear, generalship, guidance, heed, help, imprisonment, interest, maintenance, management, notice, particularity, patronage, precaution, preservation, problem, protection, prudence, regard, relief, rigor, safekeeping, shelter, supervision, support, surveillance, trust, upkeep, ward, weight
References in periodicals archive ?
The trial compared the efficacy of ALIMTA plus best supportive care versus
6%) had complete or partial responses; none of the patients on best supportive care alone had such improvements.
The aim of the study conducted at St Vincent's Hospital was to compare the outcomes of patients with liver tumours treated using radioembolisation with patients receiving standard or best supportive care alone in the setting of treatment-refractory disease.
A randomized double-blind Phase III study of RAD001 10 milligrams per day (mg/d) plus best supportive care versus placebo plus best supportive care in the treatment of patients with advanced pancreatic neuroendocrine tumor (NET).
The CHMP decision is based on the results of the pivotal Phase III GRID trial which showed that regorafenib plus best supportive care (BSC) significantly improved progression-free survival (PFS) compared to placebo plus BSC (HR=0.
PARAMOUNT: Phase III study of maintenance pemetrexed (pem) plus best supportive care (BSC) versus placebo plus BSC immediately following induction treatment with pem plus cisplatin for advanced nonsquamous non-small cell lung cancer (NSCLC).
R2 (macroscopic residual tumor) resection patients can undergo the same adjunctive treatment as R1 resection patients unless performance status is poor, in which case best supportive care is recommended.
Na Trial In Myelodysplastic SyndromE) is a Phase III, multicenter, randomized, trial of best supportive care plus rigosertib treatment compared to best supportive care alone, designed to determine the efficacy and safety of rigosertib in higher-risk MDS patients with excess blasts (5% to 30% bone marrow blasts), who are refractory, intolerant to, or have relapsed after azacitidine or decitabine treatment.
The global, randomized, double-blind REACH trial compared CYRAMZA plus best supportive care to placebo plus best supportive care as a second-line treatment in patients with hepatocellular carcinoma (HCC) after being treated with sorafenib in the first-line setting.
Results showed 34 percent of participants treated with Sylvant and best supportive care experienced tumor response, while no participant treated with placebo and best supportive care did.
Those unable to tolerate chemotherapy or who have inoperable tumors, require best supportive care.
The study is designed to assess efficacy of CRLX101 as a single agent compared to best supportive care in advanced NSCLC with overall survival as the primary endpoint.