(redirected from Beta-lactam antibiotic)
Also found in: Dictionary, Thesaurus, Medical, Encyclopedia, Wikipedia.
See: drug
References in periodicals archive ?
com)-- Bioo Scientific's MaxSignal[R] Beta-Lactam ELISA Test Kit has been validated for the screening of a wide range of beta-lactam antibiotics including ampicillin, penicillin G, amoxicillin, azlocillin, piperacillin, nafcillin, cloxacillin, oxacillin, cefoperazone, ceftiofur and other beta-lactams in a number of food matrices.
Almost all patients with positive antibodies to streptococci responded to beta-lactam antibiotics (97%).
The study by researchers at university of Notre Dame and their collaborators in Spain showed how MRSA regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics.
The properties of OP0595 and its ability to be combined with new or existing beta-lactam antibiotics promise a significant advance in the battle against increasing multi-drug-resistant bacteria.
The altered penicillin-binding protein, designated PBP2a, is able to perform its cell-wall synthesis functions, but has low affinity and does not bind to beta-lactam antibiotics.
SYN-004 is the Company's candidate therapy, currently in Phase 2 clinical trials, that is designed to degrade certain IV beta-lactam antibiotics within the gastrointestinal (GI) tract and maintain the natural balance of the gut microbiome for the prevention of C.
Adding P2A to the franchise platform expands Synthetic Biologics' intellectual property claims to cover all three beta-lactam antibiotic classes, penicillins, cephalosporins, and carbapenems.
Regardless of the origins, which are likely to become obscured as clones move back and forth between hospital and community over time, emergence of MRSA within the community is a major threat with several important clinical implications: treatment failure with accompanying complications or death may result if an antistaphylococcal beta-lactam antibiotic is used and the infecting strain proves to be resistant; infections caused by methicillin-resistant strains may be more difficult to manage or more expensive to treat, perhaps because vancomycin is inherently less efficacious (29-33); and the increasing prevalence of MRSA will inevitably increase vancomycin use, adding further to the problem of antibiotic-resistant gram-positive bacteria.
When used in combination with a beta-lactam antibiotic, these compounds can prevent resistance to the antibiotic and hence, enhance and prolong the activity of the antibiotic.
To overcome bacterial resistance to beta-lactams, current drugs combine a beta-lactam antibiotic and a beta-lactamase inhibitor.
difficile) infection, antibiotic-associated diarrhea and secondary antibiotic-resistant infections in patients receiving intravenous (IV) beta-lactam antibiotic therapy.
A two-component drug containing an AlamX inhibitor and a beta-lactam antibiotic have the potential to treat a broad spectrum of microorganisms for which no effective therapies currently exist.

Full browser ?