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Relatively few of the AD patients with gait disturbance had hypertension, the most important risk factor for vascular dementia and Binswanger's disease [1, 20].
Binswanger's disease is therefore a type of vascular dementia that can present with a clinical course similar to MID or with a slowly progressive course, clinically difficult to differentiate from dementia of the Alzheimer's type.
Initially described nearly a century ago, Binswanger's disease remains an elusive entity.