substitute

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substitute

noun agent, alternate, alternative, delegate, deputy, double, emissary, envoy, factor, lieutenant, pinch hitter, plenipotentiary, proxy, regent, replacement, representation, representative, stand-in, steward, stopgap, substitution, supplanter, surrogate, temporary expedient, trustee, understudy
See also: agent, alienate, alternate, alternative, change, commute, conduit, convert, cover, delegate, deputy, devolve, disjunctive, displace, exchange, false, imitation, intermediary, liaison, plenipotentiary, procurator, provisional, proxy, quid pro quo, replace, replacement, representative, secondary, stopgap, succedaneum, supersede, supplant, surrogate, transform

SUBSTITUTE, contracts. One placed under another to transact business for him; in letters of attorney, power is generally given to the attorney to nominate and appoint a substitute.
     2. Without such power, the authority given to one person cannot in general be delegated to another, because it is a personal trust and confidence, and is not therefore transmissible. The authority is given to him to exercise his judgment and discretion, and it cannot be said that the trust and confidence reposed in him shall be exercised at the discretion of another. 2 Atk. 88; 2 Ves. 645. But an authority may be delegated to another, when the attorney has express power to do so. Bunb. 166; T. Jones, 110. See Story, Ag. Sec. 13, 14. When a man is drawn in the militia, he may in some cases hire a substitute.

References in periodicals archive ?
Researchers across the world have been trying for years to develop a portable blood substitute that functions as an oxygen carrier, is stable enough to be stored for a prolonged period in different conditions and can be used to treat individuals of any blood type but haven't been successful so far.
According to Kundu, researchers across the world have been trying for years to develop a portable blood substitute that functions as an oxygen carrier, is stable enough to be stored for prolonged periods in different conditions and can be used to treat individuals of any blood type but haven't been successful so far due to one shortcoming.
Our studies to date have shown that HemoTech is safe, effective, inexpensive to manufacture, and convenient to administer," maintains Jan Simoni, who has served since 1993 as the Blood Substitute Group Leader and associate professor of research in the Department of Surgery, where he co-invented HemoTech along with fellow researcher Mario Feola.
The PolyHeme blood substitute safely dissipates in the body after about 24 hours, Northfield Labs said.
The interference from the blood substitute is approximately constant at -50 U/L alkaline phosphatase per 10 g/L HBOC, regardless of the activity of alkaline phosphatase.
The other problem with fluorocarbon-based blood substitutes is that they only work for about six hours, which is fine for a patient who needs extra blood quickly for an operation, but not for a patient who needs a transfusion to counteract a long-term condition like anemia.
Moore has extensive experience in domestic and global health issues and is assisting HemoBioTech in further development of HemoTech in addressing the global needs for a blood substitute and assisting the company in targeting funding opportunities on Capitol Hill in Washington DC.
Of 52 patients receiving the blood substitute, 24 (46 percent) died.
Basic laboratory methods for studying various aspects of blood substitutes (such as preparation, analysis, safety, efficacy, and animal studies) are also outlined in detail in the appropriate chapters.
Under the Phase III protocol approved by FDA, Northfield has infused surgical patients with up to six units of PolyHeme, its proprietary blood substitute.
said Tuesday it hopes to get permission to market the blood substitute in Europe within a year, and expects to apply for permission in this country in about a year.
Food and Drug Administration (FDA) for blood substitutes, the FDA indicated the need for a new generation of hemoglobin based blood substitutes and the Adenosine-GSH approach of HemoTech was cited.