There are 3 sources of blood-forming
stem cells used in transplants.
The gene therapy approach involves first obtaining blood-forming
stem cells from a patient's bone marrow.
The use of antibodies against CD117 to eliminate blood-forming
stem cells is based on studies conducted at Stanford's Institute for Stem Cell Biology and Regenerative Medicine.
How deformable cells are, and thus how stiff or squishy they are, plays an important role in retaining blood-forming
stem cells in their marrow niches and thus preserving their long-term repopulation capabilities, informed lead author Cheng-Kui Qu, MD, PhD.
The investigation, published in Nature and led by Sean Morrison, also establishes a promising approach for mapping the entire blood-forming
cells are collected from a donor's hip bone, umbilical cord, or circulating blood.
Cellerant CLT- 001 provides a hematopoietic (blood-forming
) stem cell graft free of the T cells that cause GVHD.
The artificial sweetener aspartame (Nutra-Sweet, Equal) caused lymphomas (cancers of the lymph system) and leukemias (cancers of the blood-forming
cells) in female--but not male--rats, according to a large Italian study.
Most porphyrin synthesis is located in either the liver or blood-forming
tissue, and blocks in either of these may lead to symptoms of porphyria.
stem cells from adults make blood," stated Irving Weissman, the primary researcher in the recent study.
For the first time, scientists have transformed human embryonic stem cells into primitive blood cells that are capable of maturing into specialized blood-forming
cells, an achievement that lays the foundation for new therapies using laboratory-made tissues and organs from embryonic cells.
Overexposure to lead has been shown to damage the human blood-forming
process, the nervous and reproductive systems, and the urinary tract.