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GFR decreases as glomerular filtrate outflow from the tubule is obstructed and the pressure of the increased filtrate volume in the Bowman's space opposes the forces favoring filtration.
BS] rises above 0 mmHg, as it does in nephrotic conditions where protein is filtered into the Bowman's space because of changes in the filtering membrane, GFR can increase.
As blood flows through the kidneys, approximately 20% of the plasma passes from the glomerulus into Bowman's space, forming the glomerular filtrate.