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27) Patients whose angioedema is due, at least in part, to C1 INH deficiency or dysfunction and increased bradykinin rather than histamine, would also be more refractory to antihistamines.
Low C1 INH level may be more likely to be positive (85% of HAE) than low C1 INH functional activity.
Otozomal dominat olarak kalitilan herediter C1 INH eksikliginde C1 INH proteeni kodlayan genin kromozom 11g12-g13.