Polarization of Th1/Th2 in human CD4 T cells separated by CD62L
: Analysis by transcription factors.
Differences between different markers (CCR7 versus CD62L
) and between blood samples before and after immunization were evaluated by using the Wilcoxon signed-rank test.
Influx of neutrophils into tissues begins by rolling, which is mediated via surface CD62L
(L-selectin) interacting with complementary ligands on endothelial cells, and is followed by firm neutrophil adhesion to the endothelium and consequently, transmigration (Lerman and Kim, 2015).
(L-selectin) CD134 (OX40) IL-2 receptor alpha chain (CD25) etc.
Altered gene transcription mediated by glucocorticoid- bound GR could explain reduced expression of certain plasma membrane proteins on neutrophils, such as CD62L
that is severely down-regulated in cows at parturition (Lee and Kehrli, 1998).
Apos a higienizacao dos tetos, a anti-sepsia com solucao de alcool a 70%, e descarte dos primeiros jatos de leite, coletou-se as amostras de leite para o exame bacteriologico, CCS, e para avaliacao da expressao de moleculas de adesao: L-selectina (CD62L
), [beta]2-integrina (CD11b) e CD44 pelos neutrofilos lacteos ([CH138A.sup.+]), que foram realizados por citometria de fluxo utilizando anticorpos monoclonais especificos.
These cells are characterized by the surface pattern of effector-type or effector-memory T cells (expression of CD45RA, CD11a, CD11b, CLA, [alpha]E[beta]7 and absence of CD27, CD28, CD56, CD62L
MDSCs also interrupt T cell migration to lymph nodes by releasing ADAM17, which downregulates the homing receptor CD62L
(L-selectin) onT cells .
Based on recent studies showing in vivo antioxidant effects of thymoquinone (TQ), the active ingredient of Nigella sativa seeds, this study aims to determine whether or not TQ can increase survival and sustain the expression of the homing receptor CD62L
in antigen-specific T cells in vitro.
The SHML histiocytes express monocyte/macrophage-associated antigens (CD68, HAM56, CD14, and CD64) and adhesion molecules (CD11b, CD11c, CD18, CD62L
, and CD103).
AFA Contains a Ligand for Human L-selectin(CD62L
): Using a cell-free affinity purification system in which paramagnetic Dynabeads were coated with a human L-selectin/IgGl Fc fusion protein, we captured an L-selectin binding compound from the AFA water extract (AFA-W).