Cell

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CELL. A small room in a prison. See Dungeon.

References in periodicals archive ?
Since CD8 cells weren't known to make CD4, a prerequisite for infection by the virus, the puzzling results went unexplained and to some extent ignored.
But in a small group of HIV-infected people known as long-term nonprogressors, those CD8 cells seem to stave off the development of AIDS, even in the absence of anti-HIV drugs.
But in the US study, the CD8 cells suppressed the virus without killing the healthy CD4T cells.
We will examine the effect of triggering innate responses in DC using HIV-1 mutants/drug treated wild type virus on allogeneic responses, by measurement of T cell proliferation and function and in an ex vivo CD8 T cell killing assays using peripheral blood CD8 cells from HIV-1 infected patients.
It is not able that a similar frequency of gB-tetramer positive CD8 T cells are responding, but the virus-infected WT [CD8.sup.+] T cells express 2.366-fold more KRLG-1 compared to the STAT3-deficient [CD8.sup.+] T cells, suggesting that the knockout cells are responding, but may be mostly SLEC (short lived effector CD8 cells).
After the infusion, the CD8 cells in the infected mice revived and the levels of virus in their bodies decreased by a factor of four after a month.
By looking at the numbers of CD4 and CD8 cells, checking the ratio between them and measuring the cytokine production, one can tell if a patient has HIV in only a few seconds.
The results of our study also showed that patients in meningitis/milliary group had the lowest number of CD8 cells which was significantly different from control group.
Patients in the CBSM group showed no changes in viral load, while patients in the control group showed a threefold increase in viral load over the 10 weeks of the study Patients in the CBSM group also showed significant decreases in certain types of CD8 cells.
The researchers also used a new test for HIV-specific immune function--counting the proportion of virus-specific CD8 cells by using flow cytometry to measure which of the cells produce gamma interferon in response to killed virus.
In a study of 30 women with stages Ia to IIa cervical cancer, low CD4 counts and reversal of the normal ratio of CD4 to CD8 cells were associated with rapid tumor growth and the appearance of lymph node metastases, said Dr.