Mean CD4 and CD8 cells
counts were similar in both groups of patients(P = 0.
A small case-control study determined that aging HIV-infected people (median 56 years) with a good CD4 count (median 724 cells/mm (3)) and long-term viral suppression with antiretroviral therapy have CD4 and CD8 cells
similar to those of a substantially older HIV-negative comparison group (median 88 years) and utterly unlike those of a younger HIV-negative group (median 27 years).
Since CD8 cells
weren't known to make CD4, a prerequisite for infection by the virus, the puzzling results went unexplained and to some extent ignored.
In addition, new therapeutic approaches could result from modulating or delaying the senescence of CD8 cells
in patients with HIV.
Reduced naive and increased activated CD4 and CD8 cells
in healthy adult Ethiopians compared with their Dutch counterparts.
Low densities of peritumoral infiltrates of CD3 and CD8 cells
or lowered ratios of CD8/Tregs have been reported to be useful predictive markers of progressive disease in cervical and colorectal cancers (34,58).
Patients in the CBSM group also showed significant decreases in certain types of CD8 cells
Other cells of the immune system, CD8 cells
, usually fail to defend against the virus.
Through various tests, they found that these chemicals were produced by stimulated CD8 cells
of three of the long-term non-progressors they are studying (they picked their three best non-progressors among their patients, in order to have the best chance of identifying how their cells are able to keep HIV in check).
All 60 of those studied had CD8 cells
in their bodies.
The researchers arrived at their conclusions by measuring certain components of CD4 cells and other immune-system cells known as CD8 cells