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org in the December 2017 table of contents) posed questions regarding the practices used for TT-CMV mitigation and CMV disease prevention.
To review the clinical features, management and outcome of CMV retinitis at Groote Schuur Hospital, Cape Town, SA, over a 10-year period, and to compare treatment protocols of 13 public hospitals in SA that treat patients with CMV retinitis.
Cases of probable systemic CMV infection were identified by CMV polymerase chain reaction (PCR), CMV pp65 antigenaemia test, CMV viral culture, and CMV serology.
Enzyme-linked immunosorbent assay (ELISA) was used for detection of CMV immunoglobulin G (IgG) and IgM antibodies by using commercial diagnostic kits (Human Gesellschaftfur Biochemica und Diagnosticamb H, Germany) according to manufacturer's protocol.
The CMV culture demonstrated no virus in the perilymph liquid, but CMV DNA was detected by real-time PCR in the three PCR assays performed on the sample (mean Cp value: 40.
The medical records of 142 patients with rheumatic diseases who were positive for CMV-DNA in plasma samples were reviewed, and 73 patients with CMV pneumonia were further investigated.
He developed acute postoperative renal failure requiring hemodialysis, which delayed the start of CMV prophylaxis.
In solid organ transplant recipients, CMV infection is an independent risk factor for organ rejection and nearly one-third of patients develop end-organ disease in the transplanted organ within the first three postoperative months.
Congenital CMV is one of the main causes of children being born with permanent disabilities.
You can avoid coming in contact with CMV by washing your hands often with soap and water for 15 to 20 seconds--and always after contact with diapers or a young child's saliva.