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Two classes of CNS depressants have the potential for misuse, abuse, and addiction: benzodiazepines and barbiturates.
Typically it is opioids, CNS depressants and stimulants that are the three most established chug classes that are abused.
Sangapure, Synthesis of Some Benzodiazepines and Benzothiazepines Bearing Benzofuran Moiety as Possible Cns Depressants, Ind.
However, concomitant use of alprazolam, with other CNS depressants such as alcohol and opioid analgesics, could have an additive CNS depression effect and lead to severe toxicity or even death.
Furthermore, as long-term use of CNS depressants has a tendency to suppress REM-sleep, dreams tend to creep into the waking state.
It is possible that other CNS depressants or psychotropic medications may exert similar effects on nighttime arousals as Zolpidem did in this study.
Be cautious of adverse respiratory events when prescribing atypicals alone or with any traditional CNS depressants such as benzodiazepines, sedative/hypnotics, minor tranquilizers, sleep aids, opiates, methadone, and GABAminergic agents.
It can interact with CNS depressants and stimulants, and tolerance often develops.