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idiopathic multicentric Castleman disease is a deadly subtype of Castleman disease.
Shah, Castleman disease in the pediatric neck: a literature review, Otolaryngology Head Neck Surg 2013; 148: 1028-36.
Humanized antiinterleukin-6 receptor antibody treatment of multicentric Castleman disease.
Excisional biopsy identified the mass as a hypervascular lymphoid hyperplasia consistent with the hyaline vascular type of Castleman disease.
Kaposi sarcoma-associated herpesvirus infects monotypic (IgM lambda) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders.
Example 12: Castleman Disease in the Parapharyngeal Space, Hyaline Vascular Type
Large B-cell lymphoma arising in HHV8-associaied multicentric Castleman disease.
Cervical unicentric Castleman disease presenting as a neck mass: Case report and review of the literature
The virus must actively replicate to cause and maintain Kaposi's sarcoma and multicentric Castleman disease.
Human herpesvirus 8 (HHV-8) has been detected in patients with Kaposi sarcoma, primary-effusion B-cell lymphomas, and Castleman disease (1).