Central diabetes insipidus as presenting symptom of Langerhans cell histiocytosis.
Management of
central diabetes insipidus with oral desmopressin lyophilisate in infants.
Central diabetes insipidus following intracranial hemorrhage due to vitamin K deficiency in a neonate.
Central diabetes insipidus in a dog with a pro-opiomelanocortin-producing pituitary tumor not causing hyperadrenocorticism.
In summary, we believe this represents one of the first reported cases of
central diabetes insipidus in the setting of baclofen and quetiapine toxicity, though it is not clear which drug was responsible.
Desmopressin acetate, a synthetic analogue of the natural pituitary hormone ADH, is used in the management of
central diabetes insipidus. Administration of desmopressin results in increased resorption of electrolyte-free water, with subsequently decreased urinary flow and increased urine osmolality (MicroMedex Healthcare Series, 2008).
Inadequate secretion of ADH defines
central diabetes insipidus (CDI), while the nephrogenic condition (NDI) results from an insufficient renal response to ADH.
DDAVP tablets are indicated as an antidiuretic replacement therapy for
central diabetes insipidus, and in the management of temporary polyuria and polydipsia and of primary nocturnal enuresis.
Glu-47, which forms a salt bridge between neurophysin-II and arginine vasopressin, is detected in patients with familial
central diabetes insipidus. J Clin Endocrinol Metab 1993;77:600-4.
In response, the kidney's collecting tubules absorb more water so the effective osmolality of the blood is maintained near a normal range.[62] In
central diabetes insipidus, since the kidneys fail to reabsorb water, the osmoreceptors sense dehydration.
She is receiving Na l-thyroxine (2 mcg/kg/day) for hypothyroidism, sublingual lyophilized DDAVP tablet (30 [micro]g two times a day) for
central diabetes insipidus, hydrocortisone (10 mg/[m.sup.2]/day) for adrenal insufficiency, combined estrogen-progesterone pills for hypogonadism, and a diabetic diet for diabetes mellitus.
Twenty-one (40.3%) presented with
central diabetes insipidus. The median ages of the above disorders were 43 (35-66), 36 (32-42), 64 (52-77), and 53 (39-55), respectively, with p <0.0001.
