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The CDC estimates that as many as 8 to 11 million people in Mexico, Central America, and South America have Chagas disease.
Chagas disease in a domestic transmission cycle, southern Texas, USA.
Chagas disease and leishmaniasis are classified as diseases requiring innovative and intensified disease management (IDM) given their difficultly to diagnose and treat compared to other NTDs.
cruzi is an important safety measure to help protect our blood supply and help prevent the spread of Chagas disease," said Karen Midthun, MD, acting director of FDA's Center for Biologics Evaluation and Research.
In some cases, however, especially in immunocompromised patients, acute Chagas disease may cause cardiac complications, including arrhythmia, cardiomegaly, congestive heart failure, and meningoencephalitis.
By disabling the parasite that causes Chagas disease, a simple drug might offer a way to stop this deadly condition that affects 18 million people in Latin America.
As the weather continues to warm, kissing bugs are expected to migrate north, putting more people at risk of getting Chagas disease than previously thought," said Missy Henriksen, vice president of public affairs for NPMA.
In addition, a large number of pregnant women are also infected with Chagas disease causing thousands of cases of congenital infection.
It is estimated that [approximately equal to]300,000 immigrants from Latin America, to which Chagas disease is endemic, are currently living in Japan and that [approximately equal to]34,000 births from these immigrants have occurred in the past 10 years.
and the Drugs for Neglected Diseases initiative (DNDi), a non-profit independent foundation, announced today that they have signed a collaboration and license agreement for the clinical development of a promising new drug for the treatment of Chagas disease, a fatal infectious disease that threatens 100 million people in Latin America and the Caribbean.
Chagas disease primarily affects the nervous system and the heart, causing severe neurological disorders as well as swelling or denervation of nervous tissue in the heart, colon and esophagus.