Age-dependent regulation of chromaffin cell
proliferation by growth factors, dehydroepiandrosterone (DHEA), and DHEA sulfate.
In additional ex vivo experiments, we investigated protein expression levels in the postsynaptic density (PSD) and catecholamine release from chromaffin cells
to further reveal underlying mechanisms.
As before, Lindau's group will place a chromaffin cell
in the microelectrode array and locate the secretion event.
Hains BC, Chastain KM, Everhart AW, McAdoo DJ, Hulsebosch CE, "Transplants of Adrenal Medullary Chromaffin Cells
Reduce Fore Limb and Hind Limb Allodynia in a Rodent Model of Chronic Central Pain after Spinal Cord Hemisection Injury", Exp.
Voltage-sensitive calcium flux into bovine chromaffin cells
occurs through dihydropyridine-sensitive and dihydropyridine- and omega-conotoxin-insensitive pathways.
Participation of a stress-activated protein kinase cascade in the activation of tyrosine hydroxylase in chromaffin cells
Analgesia induced by isolated bovine chromaffin cells
implanted in rat spinal cord.
PC12 cells as a model to study the effects of opiods on normal and tumoral adrenal chromaffin cells
These distinct patterns of gene expression indicate different pathways of tumorigenesis, possibly involving development of tumors from different populations of chromaffin cells
with different susceptibilities to the effects of a particular mutation.
of the adrenal medulla are derived from multipotent neural crest cells in the developing embryo.
In summary, it is essential to be aware that paragangliomas may arise from the embryonic chromaffin cells
that may have accompanied the testis; nevertheless, it is important to rule out a metastasis from other sites.
Further support for these conclusions is the result of transplant studies in which adrenal chromaffin cells
were used to prevent and/or reverse the expression of injury-induced pain behaviors [50-52].