Intratracheal
Clara cell secretory protein (CCSP) administration in preterm infants with or at risk of respiratory distress syndrome.
DC-LAMP stains pulmonary adenocarcinoma with bronchiolar
Clara cell differentiation.
Thyroid transcription factor-1, hepatocyte nuclear factor-3[beta], surfactant protein B, C, and
Clara cell secretory protein in developing mouse lung.
In a second set of experiments,
Clara cells were coexposed to Cd at different concentrations (up to 50 [micro]M final) and to 750 [micro]M 2-AF (or 4-ABP) in culture medium.
2000) treated rabbits with ipomeanol during three postnatal time periods that represent early, intermediate, and final stages of
Clara cell maturation.
A mechanism for the development of
Clara cell lesions in the mouse lung after exposure totrichloroethylene.
The authors say this may indicate that repeated exposure to disinfection by-products around indoor swimming pools damages
Clara cell function.
One of these,
Clara cell protein (CC16), is a small, 16-kDa protein produced and secreted by the nonciliated bronchiolar
Clara cells and detectable in serum.
For example, they secrete
Clara cell secretory protein (CCSP) (9), which inhibits pulmonary inflammation (10); surfactant proteins, which prevent alveolar collapse (11-15); and protease inhibitors such as secretory leukocyte protease inhibitor (SLPI) (16-18) and elafin (17,18).
8-kDa
Clara cell protein (CC16 or CC10), which is secreted in large amounts at the surface of airways from where it leaks into the serum, most likely by passive diffusion (5-8).
Dr Whitsett and his team at Cincinnatti Children's team Hospital found "good" lung cells called
Clara cells change into mucus cells in a process called metaplasia - and that the process could be reversed.
Mucinous type is composed of mucous (goblet) cells, while nonmucinous type has
clara cells and type II cells.
