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In the Supplemental Material, Table S1 summarizes DMR amplicon cleavage fragments, including CpG content and positions.
A cleavage fragment of ITIH4 from serum proteomic analysis is a candidate biomarker for detecting early-stage ovarian cancer (16).
1) Nonstandard abbreviations: DGGE, TGGE, denaturing, temperature gradient gel electrophoresis; ds, double stranded; ss, single stranded; SSCP, single-strand conformation polymorphism; HET, heteroduplex analysis; CCM, chemical cleavage method; EMC, enzyme mismatch cleavage; CFLP, cleavage fragment length polymorphism; PTT, protein truncation test; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; RT, reverse transcription; ASO, allele-specific oligonucleotide; RFLP, restriction fragment length polymorphism; PODGE, profiling of oligonucleotide dissociation gel electrophoresis; ASA, allele-specific amplification; ARMS, amplification refractory mutation system; ASPCR, allele-specific PCR; and OLA, oligonucleotide ligation assay.