depressant

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When CNS depressants are stopped abruptly, rebound effects may occur (NIDA, 2014a).
Mixed with opioid painkillers such as Valium and Vicodin, or CNS depressants such as Valium and Xanax, alcohol can slow breathing, causing respiratory failure and death.
Mixed with opioid painkillers such us OxyContin and Vicodin, or CNS depressants such as Valium and Xanax, alcohol can slow breathing, causing respiratory failure and death.
Other CNS depressants and alcohol may add to this effect.
Combination with other CNS depressants has an additive effect, increasing the risk of coma and death.
Benzodiazepines may also cause physical side effects such as vertigo and they often have additive effects when used in conjunction with other CNS depressants.