Hematological manifestations of copper deficiency
: a retrospective review.
In case of copper defiency, iron accumulates in the liver and iron availability is decreased in circulation and bone marrow; consequently, copper deficiency
causes an ineffective erythropoiesis.
(1992) showed that copper deficiency
causes hypercholesteromy because of the increase in hepatic GSH with an increase in HMG-CoA reductase activity, which is the main enzyme that regulates the synthesis of cholesterol.
In addition, imbalance of erythrocyte and serum copper was observed in II group of children with IDA with significant increase of its concentration in the blood serum, but copper deficiency
in red blood cells (Table 2).
The patient was diagnosed with copper deficiency
myeloneuropathy due to zinc toxicity from his denture adhesive.
results in anemia and congenital inability to excrete copper resulting in Wilson's disease (Gupta, 1975).
The studies reveal that there is no correlation between the copper deficiency
and the physical exercise taken (M.
Indications of copper deficiency
in a subpopulation of Alaskan moose.
The influence of experimentally induced copper deficiency
on the fertility of rams.
could be a result of either inadequate dietary intake (also termed primary copper deficiency
) or due to impairment in its uptake (secondary copper deficiency
In some geographic regions, high levels of iron, molybdenum or sulfur may tie up copper and accentuate copper deficiency
. Forages growing on alkali ground may also be low in copper and zinc.
Associations between copper deficiency
and impaired brain function were noted nearly 75 years ago.