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Caption: Figure 3: Effect of Ir-6 on cyclic nucleotide formation, LDH release, and cytotoxicity in human platelets.
Thompson, "Cyclic nucleotide phosphodiesterases: pharmacology, biochemistry and function, " Pharmacology and Therapeutics, vol.
Zagotta, "Absence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methods," Journal ofBiological Chemistry, vol.
The PDE inhibitory assay was carried out spectrophotometrically using Cyclic Nucleotide Phosphodiesterase Assay Kit (A BIOMOL[R] GREEN Quantizyme[R] Assay System, Enzo Life Sciences, Inc., New York, USA).
Cyclic nucleotides since their initial discovery have been attracting interest of researchers in physiology and biomedicine due to the ability of these compounds to act as secondary messengers.
Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responses.
Leavesley, "Can we decipher the information content contained within cyclic nucleotide signals?," J.
Effects of sildenafil on the relaxation of human corpus cavemosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes.
Lugnier, "Cyclic nucleotide phosphodiesterase (PDE) super-family: a new target for the development of specific therapeutic agents," Pharmacology and Therapeutics, vol.