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Drugs often alter laboratory test results; the literature reports >40 000 drug effects on laboratory tests (1).
Other areas explored include the application of nanotechnology in pharmacotherapy, therapeutic monitoring of antiepileptic drugs, a mathematical modeling approach for testing drug effects on the hepatitis C virus, and recent developments in drug monitoring with high performance liquid chromatography.
This approach enabled researchers to distinguish genuine drug effects from placebo reactions.
These tools are critical as we attempt to better contextualize off-target drug effects and further understand the data flowing from proteomics and transcriptomics experiments across the industry," noted Ian Humphrey-Smith, Chief Executive Officer of the Bii.
In his article, Frothingham reminds us that serious adverse drug effects in patients led to the withdrawal or restriction of 4 quinolones in the last decade and that safety may differ substantially among the quinolones discussed in Scheld's review (ciprofloxacin, gatifloxacin, levofloxacin, moxifloxacin) (2).
Using certain prescription or illegal drugs can suggest a chemical cause, since drug effects account for 25 percent of ED cases.
Surrogate markers of safety, which would speed the pharmaceutical evaluation process by detecting adverse drug effects earlier in the drug development process
Infants exposed to fluoxetine during the third trimester may have lower birth weights, while drug effects and withdrawal symptoms may occur in some neonates whose mothers take antidepressants near term.
For one thing, it was based on unsystematic clinical observation, not on the kind of pharmacological laboratory research that late-twentieth-century physicians had come to rely on for knowledge of drug effects.
In order to fully evaluate the potential for gender differences in drug effects, the MA urges that women of all ages be studied.
Because you can see change evolving so quickly with frequent scanning, you may be able to deal with much smaller numbers of patients over a short period of time when you test drug effects on patients in clinical studies," he says.

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