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Twenty-eight percent of patients were found to have underlying chronic infections, 29% had food or drug intolerance, and 21% had autoreactive urticaria.
As the number of drug intolerance episodes increased, so did the likelihood that a patient would report panic attacks, anxiety, and depression on the psychiatric surveys and scales.
For example, in patients with cystic fibrosis (CF) there is a need for alternative pulmonary therapies for lung infections due to the shortcomings of the two FDA approved nebulized antibiotics, such as decreased efficacy over long-term use, drug intolerance and new emerging pathogens.
He reported on 100 consecutive patients with severe chronic spontaneous urticaria and no known baseline psychiatric disease who were evaluated for underlying causes of the skin disease, including food or drug intolerance, chronic infection, and autoreactive phenomena.
The common mycobacteria pathogen, which causes progressive lung disease, is usually treated with a macrolide, a rifamycin, and an aminoglycoside, but drug intolerance and relapse are common reactions to these types of regimens.
2] Trials using other (non - wax-matrix) CNA products have typically reported drug intolerance due to side effects in the range of 16% to 40% of subjects.

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