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And increased physician compliance with CHF treatment guidelines will slow progression to end-stage disease.
In patients with end-stage disease, usually the result of diabetes or hypertension, kidney function typically is no more than 10% to 15%, noted Kaplan.
Despite a favorable safety and efficacy profile, the routine use of QUADRAMET for the palliation of disseminated painful bone metastases has commonly been reserved for those patients with end-stage disease when other treatment options have been exhausted," said A.
The inadequate supply of suitable donors has rapidly become the major obstacle to further extension of this life-saving therapy to patients being maintained on dialysis or dying with end-stage disease of other vital organs.
DIGNITY Trial to Combine ThermoDox([R]) with Heat to Treat End-Stage Disease
The telescope implant is the first and only treatment for AMD patients who progress to end-stage disease.
Trials of these agents versus another class of medication did not show differences in progression to end-stage disease or other indicators of function.
Despite the past decade of advancements in macular degeneration therapies, retina specialists still did not have a treatment for the many wet and dry AMD patients who progressed to end-stage disease," said Julia A.
Asymptomatic patients who are at high risk for developing heart failure are classified as stage A; asymptomatic patients with cardiac structural abnormalities or remodeling are considered stage B; patients with current or prior symptoms are stage C; and patients with refractory end-stage disease are stage D.
Future clinical trials should exclude patients with stable minimal to moderate and end-stage disease to ensure maximum response to therapy.
Grekos is taking his groundbreaking work in regenerative biomedical technology to an international arena that has never before seen the dramatic clinical success achieved with his end-stage disease patients.
If we are going to have effective therapies, they need to be working in patients before they get to end-stage disease.