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Hepatitis C Virus (HCV) is a chronic disease of liver which ultimately leads to Hepatic Steatosis, Cirrhosis and Liver Cancer.1 According to worldwide study, more than two hundred million people are infected by HCV.2 HCV is single-stranded (ss) RNA enveloped virus, which is being placed in family flaviviridae.3 Six major genotypes of HCV has been identified, which diverge by approximately 30-34% at the nucleotide sequence level, and several subtypes throughout the world.
RSV is a 15 kb negative sense RNA enveloped virus with both spherical and helical structural forms, and therefore has greater genomic and structural similarity to Ebola virus (19 kb negative sense enveloped helical RNA virus) than HCV (9.6 kb positive sense enveloped icosahedral RNA virus) and despite its lability has been shown to contaminate fomites (26).
HCV, a positive sense single-stranded RNA with 9.6 kb size, is an enveloped virus belonging to family flaviridae having six genotypes with various subtypes and works to some extent for its survival by limiting the interferon-signaling pathway3.
Nonwovens disinfectant products have a higher potency than what is normally required for an enveloped virus, such as Ebola.
Under an electron microscope, the coated nanodevices closely resembled an enveloped virus. Perrault then demonstrated that the new nanodevices survived in the body.
The a priori belief that enveloped virus structures must encode a fusion loop and penetrate cells by fusion, now dominates the field to the exclusion of alternate modes of virus entry.