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Cartilage degradation, the main feature of OA, is mainly mediated by extracellular matrix degrading MMP enzymes [13].
But in some women's breasts, collagen, elastin and other extracellular matrix proteins form thick ropes of connective tissue that appear as stringy white material on a mammogram.
Ultrastructural localization of extracellular matrix components in human retinal vessels and Bruch's membrane.
Smooth muscle cells possess the contractile apparatus of actin and myosin filaments and the cytoskeleton with the membrane skeleton, which provides the interface between the contractile machinery on the inside of the cell and the extracellular matrix on the outside, to which force must be transmitted.
The integrin-binding peptide, GRGDSP, is thought to decrease LTP by competing for integrin binding sites in the extracellular matrix that recognize the RGD motif; successful binding by the peptide then disrupts normal integrin function during LTP expression and maintenance.
I argue that the developmental role of the extracellular matrix (ECM), a comilex set of molecules including collagens, is a primitive feature of multicellularity in animals, and that it provides evidence that animals are monophyletic and derived from a common multicellular ancestor (Fig.
Aziyo's biologic extracellular matrix for vascular repair is constructed from a multi-laminate sheet of decellularized, non-crosslinked, lyophilized extracellular matrix (ECM) derived from pig small intestinal submucosa (SIS).
The resulting oxidative stress increases inflammation and triggers the excessive release of enzymes called matrix metalloproteinases (MMPs) that degrade extracellular matrix components that provide skin integrity and structure.
Among their topics are the composition and function of interstitial fluids; the extracellular matrix, basement membrane, and glycocalyx; the biochemistry of hyaluronan in the interstitial space; proteolysis in the interstitium; the fibronolytic system in the interstitial space; kallikrein; matrix metalloproteinases in the interstitial space; coagulation factors in the interstitial space; and protease inhibitors.
Clinical use of intact allogenic or xenogenic extracellular matrix (ECM) facilitates tissue regeneration.
Rich in sulfated galactans derived from the Hypnea musciformis algae, this novel ingredient is said to protect the cytoskeleton by maintaining vimentin organization and preserving synthesis of the extracellular matrix proteins; as well as support the matrix network by stimulating the formation of collagen and fibrillin networks.

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