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In this context, we conducted a series of in vitro experiments aimed at evaluating the potential cytotoxic activity exerted by EUG on three different human cancer cell lines and its potential regulatory effect on FOXM1 protein levels.
Inhibition of FOXM1 transcription factor suppresses cell proliferation and tumor growth of breast cancer," Cancer Gene Therapy, vol.
Although designing drugs is a huge challenge, the discovery will allow researchers to create molecules that mimic thiostrepton but are even more effective at blocking the effects of FOXM1.