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Facilitated diffusion suggested a benign aetiology while restricted diffusion was suggestive of malignancy.
Interestingly, glucose transport occurs through both endothelial cells by facilitated diffusion and by GLUT 1 and GLUT 3 transporters [44, 45] present on the surface of neurons and endothelial cells.
9) In active lesions a central core of facilitated diffusion often exists with a rim of diffusion restriction at the advancing edge which is typically incomplete.

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