If a subject with DCM had any first-degree relative
who was also affected with DCM, those first-degree relatives
were invited for screening for DCM by history, physical examination, electrocardiogram (ECG), echocardiography and cardiac catheterisation where indicated.
"The present findings document that first-degree relatives
of individuals with autism demonstrate a unique pattern of oculomotor impairments similar to that previously reported in independent samples of individuals with autism, suggesting that these alterations within sensorimotor and cognitive brain circuitry may be familial traits," the authors said.
"About 25% to 30% of breast cancer is family clustered, but the incidence of breast cancer in the family is not very useful in predicting if you will get breast cancer yourself." At present, having a first-degree relative
diagnosed with breast cancer before age 40 is considered to be an indication for starting breast cancer surveillance before age 50, Dr.
Methods: Fifty-five obese women and their 154 first-degree relatives
(daughter, son, sister, brother), 60 non-obese women and their 100 first-degree relatives
were enrolled in this cross-sectional controlled study.
Researchers at Spectrum and DeVos Children's Hospital, also in Grand Rapids, found that 95% of children thought to have fetal alcohol effects also had psychiatric or behavioral disorders and that 89% had a first-degree relative
with a psychiatric or behavioral disorder.
The presence of one or more attacks of vertigo in first-degree relatives
of the patients was accepted as a positive family history for episodic vertigo.
, including sisters, have about twice the risk as the average woman of developing breast cancer.
The research team then performed extensive cardiovascular testing on 109 of 147 available first-degree relatives
of the victims.
The simultaneous presence of autoantibodies to all three antigens strongly predicts type 1 diabetes in first-degree relatives
of individuals with the disease (9).
Kinship of the carers was identified and divided into three groups as follows: spouses; first-degree relatives
, most of whom were adult children; second-degree relatives and some unrelated carers.
This supports the idea that people with first-degree relatives
who have, or had, the disorder are at greater risk for developing the disease.
The persons who should be screened are the first-degree relatives
(parents, brothers, sisters, and children) of persons with FMEN1, since these family members are at 50-50 risk of already having inherited the FMEN1 gene.