Plotkin et al., "Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration
," Human Molecular Genetics, vol.
Fox, "A volumetric magnetic resonance imaging study of the amygdala in frontotemporal lobar degeneration
and Alzheimer's disease," Dementia and Geriatric Cognitive Disorders, vol.
Sample autopsy signout for Example 4, hippocampal sclerosis and TAR DNA-binding protein 43 kDa (TDP-43) in late-onset frontotemporal lobar degeneration
Assessment of socioemotional processes facilitates the distinction between frontotemporal lobar degeneration
and Alzheimer's disease.
Frontotemporal lobar degeneration
is a brain disorder that typically leads to dementia and sometimes occurs in tandem with ALS.
PICK'S disease is a rare neurodegenerative disease that causes progressive destruction of nerve cells in the brain due to frontotemporal lobar degeneration
. Symptoms include loss of speech and dementia.
Engelborghs et al., "The genetics and neuropathology of frontotemporal lobar degeneration
," Acta Neuropathologica, vol.
Washington, December 27 ( ANI ): MRI can effectively and non-invasively screen patients for Alzheimer's disease or Frontotemporal Lobar Degeneration
(FTLD), according to a new study.
(2) Frontotemporal lobar degeneration
is a broad diagnostic term that encompasses multiple distinct forms of a dementia syndrome, with the three major subtypes being frontotemporal dementia, semantic dementia (concept based memory loss), and primary progressive aphasia.
Pick's disease accounts for the largest proportion (at least 70%) of patients with frontotemporal lobar degeneration
; the disease is characterized by the presence of Pick bodies, protein tangles in neuronal tissues.
TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
. FEBS J 2011;278:3539-49.
Alzheimer's disease and frontotemporal lobar degeneration
(FTLD) are two of the most prevalent forms of neurodegenerative disorders.