They found that GFR
and RPF was normal in all malnourished children.
In the present study, kidney function of obese participants was assessed with Cr-based, cystatin C-based, combined Cr and cystatin C and BCM-based GFR
formulae and with proteinuria levels.
The new Asian modified CKD-EPI equation leads to more accurate GFR
estimation in Chinese patients with CKD.
(ml/min)=(%renal uptakex9.8127)-6.82519 (Equation 1)
Group 1: GFR
[greater than or equal to]90 mL/min/1.73 [m.sup.2].
A total of 687 children, comprising 375 (54.58%) males and 312 (45.41%) females, were studied for the GFR
Mean serum creatinine was 165.7 [+ or -] 60 [micro]mol/L, cystatin-C was 1.6 [+ or -] 0.5 mg/l, and mean measured GFR
was 41.2 [+ or -] 18.9 ml/min/ 1.73 [m.sup.2].
Updated Schwartz is derived from the children with GFR
range of 15-75 ml/min/1.73 m2 using Iohexol clearance, so its application to children with mild renal insufficiency is also questionable.5 SHID equation is adjusted for age so it can be used in children.
* Kidney health is evaluated using laboratory measurements to estimate function (GFR
) and damage (proteinuria).
is defined as the clearance of a substance in the plasma which is exclusively metabolized by the kidneys and freely filtered by the glomeruli2.
The MDRD and the CKD-EPI are newer equations that are at least validated to real GFR
and not creatinine clearance.
Among the significant additions made by KDIGO were the inclusion of urine albumin, also called micro-albumin, as a key factor in assessing CKD, whereas, previously, the disease had been predominantly diagnosed using creatinine and GFR
. The cause of the CKD was also considered in classification of the patient.