Mutation

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MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.

References in periodicals archive ?
What we know is that if you have a gain of function mutation in CARD 14, we think that this activates the NFkB pathway and leads to increased inflammation of the skin.
Hematopoietic stem cell transplantation in patients with Gain of Function STAT1 Mutation,".
Finally, it has been reported that autoimmunity findings could be controlled with ruxolitinib (Janus kinase inhibitor) in patients with gain of function STAT1 mutation (38).
CYP2C19 loss of function (LOF) and gain of function (GOF) genotype, adenosine 5′-diphosphate (ADP)-channel platelet inhibition rate (PIR) tested by TEG and the occurrence of 3-month major adverse cardiovascular events and ischemic events were assessed in 116 patients.
MDA-MB-468 cell line is hemizygous for a mutated p53 gene which makes a R273C mutant and ectopic expression of WT TP53 in these cells cannot overcome the gain of function of mutant form (18) This mutant TP53 protein is reported to cooperate with oncogenes for transforming cells and inhibits p73 protein (14).