To measure the strength of association between ER-[beta]
gene promoter (rs3020449, rs3020450, rs1271572) and exon polymorphisms (rs4986938 G/A+1730 and rs1256049 G/A1820) with uterine leiomyomas, odds ratios (OR) and their 95% confidence intervals (CI) were calculated.
For example, we have previously shown that methylation change at a single CpG site within the ADAMTS4
gene promoter also associates with PT (El Khoury et al., 2018).
Investigation of Interleukin 1 Alpha
Gene Promoter Polymorphism in hemodialysis patients with arteriovenous fistula thrombosis.
It is noted that the 5 -end of the gene-specific reverse primer was designed immediately upstream of the porcine PBD3 mRNA reference sequence (GenBank accession number NM_214444), and the entire PBD3
gene promoter fragment is located at chr15: 38,063,074-38,064,194 of the UCSC Genome Browser assembly ID susScr11.
Kuo, "Hypermethylation of the CDKN2a
gene promoter is a frequent epigenetic change in periocular sebaceous carcinoma and is associated with younger patient age," Human Pathology, vol.
Usually, the methylation status in the
gene promoter will affect the gene expression at the mRNA level; for example, the hypermethylated status in the
gene promoter will inhibit the gene expression.
Ali et al., "Matrix metalloproteinase-1
gene promoter polymorphism and risk of ovarian cancer," Journal of the Society for Gynecologic Investigation, vol.
In this work, we present for the first time the isolation and characterization of HSPA6
gene promoter region from the Arabian camel.
As shown in Figures 2 and 4, the mean (sd) methylation levels of the CHN2
gene promoter in the case group were significantly higher than in the control group, which were 2795.55 (733.19) and 1026.73 (698.73), respectively, showing significant differences between the two groups (t=21.25, p<0.001).
The current study was planned to assess the associations of genotype and allele frequencies by detecting AVPR1A
gene promoter SNPs-6951 locus in type I HRS patients, in order to identify molecular markers of HRS early detection.
(a, c) MSP analysis of the methylation status of BARF1 and BHRF1
gene promoters before 5-Aza-CdR treatment in EBV-positive cell lines: PT, GT38, C666-1, Raji, GT39, SNU719, B95-8, and OB.
Wang et al., "The interactions between alcohol consumption and DNA methylation of the ADD1
gene promoter modulate essential hypertension susceptibility in a population-based, case-control study," Hypertension Research, vol.