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Related to Glutamic acid decarboxylase: Glutamic Acid Decarboxylase Antibody, GAD65
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Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase.
Mice lacking the 65 kDa iso-form of glutamic acid decarboxylase ([GAD.
These five islet autoantibodies are islet cell cytoplasmic autoantibodies (ICA); insulin autoantibodies (IAA); glutamic acid decarboxylase autoantibodies (GADA); insulinoma associated-2 autoantibodies (1A-2A); and zinc transporter-8 autoantibodies (ZnT8A).
Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for National Institute of Diabetes and Digestive and Kidney Diseases consortia.
Association between glutamic acid decarboxylase genes and anxiety disorders, major depression, and neuroticism.
The most common islet autoantibodies, which are islet cell autoantibodies (ICAs), glutamic acid decarboxylase (GAD) autoantibodies, insulinoma-associated antigen 2 (IA-2) autoantibodies, and insulin autoantibodies, are found in childhood T1D patients, and many of these patients demonstrate positivity for multiple islet autoantibodies.
Of the 535 children who were screened for inclusion in the TODAY study, approximately 5% had only glutamic acid decarboxylase (GAD) autoantibodies and 6% had only IA-2 autoantibodies.
The group has found antibodies against the enzyme glutamic acid decarboxylase in the spinal fluid and blood of a woman with the disease.
Both TrialNet studies aimed to preserve secretion of insulin, the hormone that controls blood glucose levels; one with the drug abatacept, and the other with a vaccine called glutamic acid decarboxylase (GAD).

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