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Our intent was also to stimulate thinking about the potential threat of increased HBV/HCV transmission among displaced people, with particular reference to IDPs from NWA, and to encourage timely interventions to prevent a worsening HBV and HCV epidemic both in IDPs and hosting communities.
HBsAg level may reflect the transcriptional activity of cccDNA as well as integrated HBV DNA mRNA production and translation to HBsAg (truncated) rather than the absolute amount of cccDNA.
Lately, real time PCR (RT-PCR) has been widely used for HBV DNA detection and quantification.
Between July 2007 and July 2009, HBV chronically infected patients were recruited from the Hepatitis B Outpatient Clinic of the Clinical Hospital of the Faculty of Medicine of Ribeirao Preto, University of Sao Paulo (HC FMRP USP).
Conclusions: Chronic HBV infection was associated with low BMD and increased the risk of developing subsequent osteoporosis.
Based on what is understood about HBV infection, increasing the potency of nucleoside analogues, which are the mainstay of current HBV therapy, will only go so far toward absolute cure.
Cirrhosis of liver and hepatocellular carcinoma (HCC) are the potential end points of silent chronic HBV infection.
In preclinical HBV infection assays, CpAMs has shown to suppress both viral replication and the cccDNA formation associated with viral persistence.
ID-NAT is a multiplex assay that provides simultaneous detection of HIV, HCV RNA, and HBV DNA.
Why HBV and other communicable diseases are on the rise in Pakistanis can be answered by lack of education about spread of major communicable diseases including HBV, HCV and HIV, scanty health care facilities in rural areas, low socioeconomic state of majority and some social and cultural constrains9.
To study the association of different risk factors for transmission of HBV infection in persons with occult HBV infection
However, since the introduction of ART, the proportion of deaths due to HBV-associated end-stage liver disease (ESLD) has increased [7] because progression of HBV infection towards cirrhosis, ESLD and hepatocellular carcinoma is more rapid in HIV-coinfected patients.