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Liberti et al (1994) reported that the mean areas of the Hassall's Corpuscles increased with the foetal age, with the greatest observable difference between 16th to 19th and 20th to 23rd weeks.
Liberti EA, Fagundes T P, Perito M A, Matson E, Konig Junior B: On the size of Hassall's corpuscles in human fetuses.
Hassall's Corpuscles in the thymus of foetuses, infants and children: immunological and histochemical aspects.
Hassall's corpuscles in the thymus are formed from degeneration of compact masses of reticular cells.
The study reflects on the changes in the thymus and shows that the thymus weighs the most during puberty and also has the maximum number of Hassall's corpuscles during the same period.
Medulla exhibited a number of Hassall's corpuscles which varied in size and shape.
To investigate this possibility, the number and length of Hassall's corpuscles was also determined.
Similarly the diameter of Hassall's corpuscles was measured along its long axis through 100x objective in three randomly selected different fields.