Condition Genotype Phenotype MCV& MCH Silent carrier [alpha][alpha]/ Asymptomatic Normal [alpha] - Minor [alpha] -/ Asymptomatic Decreased [alpha] -; [alpha] [alpha]/ - - Hb H disease [alpha] -/-- Moderate hemolytic Decreased anemia
Hydrops fetalis --/-- Incompatible with Decreased postnatal life Table 5.
(7) Less common features include hepatic fibrosis,
hydrops fetalis, and renal failure.
The 20 chapters explain perinatal autopsy, techniques, and classifications; placental examination; the fetus at less than 15 weeks gestation; stillbirth and intrauterine growth restriction;
hydrops fetalis; the pathology of twinning and higher multiple pregnancy; patterns in genetic conditions; the metabolic disease autopsy; the abnormal heart; the central nervous system; significant congenital abnormalities of the respiratory, digestive, and renal systems; skeletal dysplasias; congenital tumors; complications of prematurity; intrapartum and neonatal death; sudden unexpected death in infancy; infections and malnutrition; the role of magnetic resonance imaging and radiology in post mortems; and the forensic post mortem.
However, for women who aren't immune, contracting the infection during the first 20 weeks of pregnancy increases the risk of miscarriage and of the baby developing
hydrops fetalis, a serious condition in which there's anaemia, heart failure and tissue swelling.
Fetal anasarca also called
hydrops fetalis is a rare clinical condition in canines though seen most commonly in cattle and may affect sheep (Roberts, 1971).
Four gene deletions (--/--) result in significant production of hemoglobin Barts (Hb Barts) that usually results in fatal
hydrops fetalis [6,7].
Only four prenatal tests were performed for [alpha]-thalassaemia, two for a Chinese family, where both parents were carriers of a [--.sup.SEA] mutation and they had three previous stillborn infants with
hydrops fetalis. One fetus was found to be a carrier, the other unaffected.
We decide to deliver the baby due to
hydrops fetalis, and a cesarean section was performed one day after the mother's examination.
Hydrops fetalis is a serious condition which indicates poor prognosis for the affected fetus.
Hydrops fetalis describes the fetus with generalized subcutaneous edema and fluid collections in some or all serous cavities.
Diagnosis and management of early non-immune
hydrops fetalis. Prenat Diagn 1997;17: 1261-8.
The detection of anemia in RI fetuses is the most important point in the treatment of immune
hydrops fetalis. Invasive techniques such as amniocentesis (AC) and cordocentesis (CC) used to identify the fetuses with severe anemia [4-5].
