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The combined use of intralesional TAC and 5- FU in the treatment of inflamed hypertrophic scars has previously been reported to be effective and can avoid these potential complications.2 Transient burning sensation or pain was the most common immediate adverse effect reported by all patients at the TAC+5-FU- and 5-FU-treated segments which is consistent with other studies.2,11,13,14
Some authors suggest that these hypertrophic scars may, in fact, be early recurrent keloids.
Fitzpatrick, "There is an indisputable need for better treatments for keloids and hypertrophic scars, ones that shrink the scar without the unpleasant side effects."
In this study there were 24 patients having keloid / hypertrophic scar on the body and having consent for surgical excision followed by application mitomycin-c on resected bed.
Keloids and hypertrophic scars: Review and treatment strategies.
Hypertrophic scars usually are pink in color and firm to the touch, and are limited to the borders of the original wound.
"We know that every time we treat a hypertrophic scar, it will get better," she added.
Follow-up on treatment of hypertrophic scars and keloids with triamcinolone.
Such studies might lead to improvements in the application vehicle and in the prevention of hypertrophic scars over the long term.
[12.] Seo SH, Sung HW.J Eur Acad Dermatol Venereol, Treatment of keloids and hypertrophic scars using topical and intralesional mitomycin C.
Hypertrophic scars rather frighteningly go on thickening for up to six months and may be itchy or painful.