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Since the new non-benzodiazepine hypnotics increase slow wave sleep, the likelihood of inducing sleepwalking or other sleep behavior increases in people with a history of sleep walking.
The findings, which support those of numerous prior studies that also suggested a link between hypnotics and increased mortality and between hypnotics and cancer, are important given that hypnotic drugs are among the most widely used treatments in medicine; an estimated 6%-10% of adults in the United States used hypnotics in 2010, the investigators reported.
Study participants who took sleeping pills were matched with control patients of similar ages, gender and health who received no hypnotics in order to eliminate the possibility that other factors led to the results.
Most patients who were not taking antidepressants took hypnotics for 4 weeks or less (60%-70%).
These studies suggest that transient and short-term insomnia -- sleepless nights brought on by excitement or stress -- can be effectively treated with lower doses of hypnotics.
Having a current prescription for a hypnotic was associated with a four-fold increase in suicide risk in the adjusted model".
In 1993, zaleplon (Sonata) was the first pyrazolopyrimidine investigated for clinical use as a hypnotic.
Most subjects had tried at least once before to stop their taking of hypnotics, without success.
It seems these numbers are probably low considering the number of prescriptions for hypnotics written in the United States, which is steadily increasing every year.
Historically, there have been two reasons for this disinclination to use hypnotics in combination with antidepressants.
Avidan went on to speculate that the use of hypnotics to treat insomnia in the frail elderly might actually protect against falls, Dr.