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Related to Immune rejection: Organ rejection
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The researchers discovered that the combination of these two molecules allowed the allogeneic cells to survive in humanized mice without triggering an immune rejection.
In December 1998, Harold Varmus, then head of the National Institutes of Health, acknowledged during Senate testimony that immune rejection had to be overcome before stem cells could be used for transplantation, but he suggested that we might be able to do so without resorting to autologous stem cell transplantation.
If hESC-derived hematopoietic cells prove to be a scalable way to prevent immune rejection, this will certainly benefit our approach, and could obviate the scientific rationale for patient-specific therapies that are based on adult stem cells or nuclear transfer.
There is a second technology for obtaining stem cells, one that has neither the problem of immune rejection in its future, nor -- in my opinion at any rate - the taint of a lost soul in its design.
As with more conventional types of transplants, immune rejection is a major potential problem.
To avoid the problems of immune rejection, scientists might establish a bank of human embryonic stem cells that would match almost anyone in the population.
4) The prevention of immune rejection of transplanted cells.
There is no fully effective treatment for the conditions but the transfer to the patient of "clean cells" of their own type would ensure there would be no immune rejection.
Because animals like pigs are quite different from humans, their organs would probably trigger a very strong immune rejection.
While they can be effective, they are also associated with some risks of both tumor growth and immune rejection.
PEC-01 cells are delivered under the skin in the Encaptra drug delivery system, a proprietary device with a selectively porous cell-impermeable membrane, which is designed to protect the implanted cells from possible immune rejection, to permanently contain the cells and prevent their distribution away from the implantation site, as well as to provide a platform for product vascularization.