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Related to Immune tolerance: hypersensitivity, autoimmunity
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For examining the maintenance of humoral immune tolerance, the tolerant recipient C3H mice 6 weeks after tolerance induction received intravenous injection of Balb/c spleen cells (2 x [10.
Regulatory T cells(Tregs) are key players in the maintenance of peripheral immune tolerance through suppression of the proliferation and release of proinflammatory cytokines from immune cells.
The Immune Tolerance Network is a nonprofit, government-funded consortium.
Other areas covered include immune tolerance in stem cells, stem cells in atherosclerosis, and high-dose immunosuppression with autologous stem cell transplantation in severe refractory systemic lupus erythematosus.
Overall, this study gives important preliminary information on techniques that may enable us to overcome immune tolerance in the development of early tumours by using dendritic cells pulsed with HER-2 HLA class 1 and 2 peptides.
Also discussed is how B-cell survival factors may contribute to the loss of immune tolerance that leads to pathologic autoimmunity.
Accordingly, the joint research group has concluded that the transgenic rice has a property to effectively induce oral immune tolerance.
The Edmonton experience has since been replicated in an as yet unpublished 10-center study conducted by the National Institutes of Health-sponsored Immune Tolerance Network.
The natural recovery from food hypersensitivity in the majority of allergic babies with age suggests that immune-mediated reactions resulting from immature digestion, gut integrity and mucosal immune tolerance are reversible as the infant gut matures.
In addition to the new research data, Geron announced that it has licensed intellectual property rights from two research institutions for these hematopoietic cells and the approach of using them to achieve immune tolerance to hESC-derived transplants.

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